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. 2017 Oct 3;10:4809–4819. doi: 10.2147/OTT.S140886

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© 2017 Li et al. This work is published and licensed by Dove Medical Press Limited

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Kaempferol downregulates the mRNA levels of EMT markers and MMPs in TNBC cells.

Notes: (A, B) MDA-MB-231 TNBC cells were incubated with 20 μmol/L kaempferol for 1 h, and then subjected to the qPCR assays. The relative mRNA levels of E-cadherin, Vimentin, Snail, Slug (A), and MMP2, MMP9 (B) were normalized to the average value of controls. Results are presented as mean ± SD of 3 independent experiments.

Abbreviations: EMT, epithelial–mesenchymal transition; MMP, matrix metalloproteinase; qRT-PCR, quantitative real-time polymerase chain reaction; TNBC, triple-negative breast cancer.