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. 2017 Oct 3;9:595–607. doi: 10.2147/CEOR.S146280

Table 4.

Comparison of demographic and treatment characteristics

GT1 patients
GT3 patients
IFN-based treatment (n=17) IFN-free treatment (SOF + LDV)a (n=100) IFN-based treatment (n=10) IFN-free treatment (SOF + DCV)b (n=100)
Demographics
Genotype, %
 1a 53 67 N/A N/A
 1b 41 31 N/A N/A
 Unconfirmed 6 2 N/A N/A
Male, % 53 59 60 57
Mean BMI 28 27 26 27
Cirrhosis, % 24 16 10 19
Treatment
Treatment duration (weeks), mean ± SD 32.9 ± 11.6 12.0 ± 0 33.4 ±12.15 14.28 ± 4.7

Notes:

a

Derived from ION-I trial (Afdhal et al18).

b

Derived from ALLY-3 trial (Nelson et al19).

Abbreviations: BMI, body mass index; DCV, daclatasvir; GT1, genotype 1; GT3, genotype 3; IFN, interferon; LDV, ledipasvir; N/A, not applicable; SD, standard deviation; SOF, sofosbuvir.