Table S6.
Comparison of medical resource utilization and costs for GT3 patients
| Resource item | Patients receiving IFN-based therapy (n=10)
|
Theoretical patients receiving SOF/DCV (n=100)
|
||
|---|---|---|---|---|
| Mean number per patient ± SD | Mean cost per patient ± SD | Mean number per patient ± SD | Mean cost per patient ± SD | |
| Blood tests | 13.5 ± 5.56 | $1555.69 ± 399.33 | 4.16 ± 0.37 | $486.25 ± 27.95 |
| Ultrasound | 0.10 ± 0.32 | $3.75 ± 11.84 | 0 ± 0 | $0 ± 0 |
| CXR¶ | 0.30 ± 0.48 | $15.72 ± 23.58 | 0 ± 0 | $0 ± 0 |
| CT scan | 0.10 ± 0.32 | $29.50 ± 93.29 | 0 ± 0 | $0 ± 0 |
| ECG¶ | 0.10 ± 0.32 | $1.56 ± 4.92 | 0 ± 0 | $0 ± 0 |
| Urinalysis | 0.10 ± 0.32 | $2.06 ± 6.50 | 0 ± 0 | $0 ± 0 |
| Bone scan | 0.10 ± 0.32 | $66.74 ± 200.23 | 0 ± 0 | $0 ± 0 |
| Sputum MCS | 0.10 ± 0.32 | $3.38 ± 10.67 | 0 ± 0 | $0 ± 0 |
| RFTs | 0.10 ± 0.32 | $3.57 ± 11.27 | 0 ± 0 | $0 ± 0 |
| Rib resection | 0.10 ± 0.32 | $35.67 ± 112.78 | 0 ± 0 | $0 ± 0 |
| Stress ECG¶ | 0.10 ± 0.32 | $15.22 ± 48.11 | 0 ± 0 | $0 ± 0 |
| Specialist Referral | 0.60 ± 0.97 | $105.89 ± 147.65 | 0 ± 0 | $0 ± 0 |
| Psychiatry | 0.20 ± 0.42 | $52.06 ± 109.75 | 0 ± 0 | $0 ± 0 |
| Cardiology | 0.10 ± 0.32 | $15.09 ± 47.72 | 0 ± 0 | $0 ± 0 |
| Cardiothoracic surgery | 0.10 ± 0.32 | $8.56 ± 27.05 | 0 ± 0 | $0 ± 0 |
| Thoracic medicine | 0.10 ±0.32 | $15.09 ± 47.72 | 0 ± 0 | $0 ± 0 |
| Infectious diseases | 0.10 ± 0.32 | $15.09 ± 47.72 | 0 ± 0 | $0 ± 0 |
| Liver clinic visits | 10.5 ± 2.46 | N/A | 4.76 ± 1.58 | N/A |
| ER presentations | 0.50 ± 0.97 | N/A | 0.02 ± 0.14 | N/A |
| Hospital admissions | 0.10 ± 0.32 | N/A | 0 ± 0 | N/A |
Abbreviations: CT, computed tomography; CXR, chest x-ray; DCV, daclatasvir; ECG, electrocardiogram; ER, emergency room; GT3, genotype 3; IFN, interferon; MCS, microscopy, culture and sensitivities; N/A, not applicable; RFTs, respiratory function tests; SD, standard deviation; SOF, sofosbuvir.