. 2017 Aug 3;56(11):2512–2526. doi: 10.1002/mc.22698

Table 2.

Transcription factors significantly associated with altered CRC survival prior to adjustment for multiple comparisons

	Number of miRNAs associated with TF			Differential expression (carcinoma—normal mucosa)
Gene	P _raw < 0.05	P _adj < 0.05	miRNA with FC > 50%	Q1	Q3	HR ^a	(95% CI)	P‐value	Q‐value
ATF1	359	238	46	−0.01	0.75	0.54	(0.33, 0.87)	0.011	0.082
BACH1	311	160	35	−0.03	0.70	0.63	(0.41, 0.96)	0.039	0.082
BCL11A	232	72	23	−0.09	0.57	0.64	(0.43, 0.95)	0.028	0.082
BCLAF1	200	24	13	−0.13	1.00	0.65	(0.42, 0.99)	0.049	0.082
CTCF	306	143	32	0.01	0.87	0.64	(0.44, 0.93)	0.022	0.082
EGR1	102	0	0	−0.87	0.92	0.58	(0.39, 0.88)	0.015	0.082
ELF1	340	226	45	−0.07	1.16	0.61	(0.40, 0.94)	0.030	0.082
ELK1	239	86	16	0.09	0.97	0.67	(0.46, 0.98)	0.046	0.082
ETS1	104	5	3	−0.43	0.57	0.56	(0.36, 0.86)	0.010	0.082
FOS	97	0	0	−1.39	0.43	0.61	(0.41, 0.92)	0.022	0.082
GABPA	340	195	46	−0.03	0.48	0.60	(0.36, 0.99)	0.048	0.082
HDAC6	374	283	40	−0.15	0.38	0.70	(0.51, 0.97)	0.042	0.082
HDAC8	203	10	3	−0.06	0.55	0.53	(0.32, 0.86)	0.011	0.082
HMGN3	314	164	41	−0.25	0.93	0.56	(0.33, 0.95)	0.030	0.082
IRF1	122	0	0	−0.38	0.71	0.43	(0.25, 0.74)	0.003	0.082
JUN	204	20	1	−0.22	1.19	0.55	(0.35, 0.86)	0.012	0.082
JUNB	222	22	4	−0.48	1.07	0.63	(0.41, 0.97)	0.039	0.082
JUND	220	60	1	−0.65	0.67	0.61	(0.41, 0.90)	0.017	0.082
MEF2A	278	142	34	−0.23	0.52	0.62	(0.43, 0.90)	0.016	0.082
MXI1	208	23	2	−0.32	0.35	0.63	(0.44, 0.90)	0.017	0.082
NFYA	351	228	37	−0.06	0.77	0.65	(0.44, 0.95)	0.035	0.082
PHF8	266	120	21	−0.15	0.62	0.65	(0.44, 0.98)	0.046	0.082
RBBP5	344	211	43	−0.04	0.64	0.61	(0.38, 0.98)	0.041	0.082
SMARCC1	352	235	46	0.32	1.51	0.65	(0.44, 0.96)	0.034	0.082
SMARCC2	338	207	38	−0.22	0.98	0.63	(0.41, 0.95)	0.036	0.082
SP1	306	150	34	−0.18	0.97	0.62	(0.41, 0.96)	0.036	0.082
STAT5A	252	68	14	−0.14	0.51	0.57	(0.37, 0.87)	0.010	0.082
TCF12	379	251	46	−0.10	0.98	0.62	(0.38, 0.98)	0.048	0.082
ZBTB33	320	105	29	0.10	1.03	0.59	(0.38, 0.92)	0.021	0.082
ZNF263	317	174	26	0.01	0.90	0.66	(0.45, 0.97)	0.040	0.082

^{^a}

Adjusted for age, center, sex, and AJCC.