Table 6.

Pathways associated with TFs that are associated with survival and miRNA expression

TF	Number of pathways	Pathways a
ATF1	7	ERK/MAPK Signaling, Role of BRCA1 in DNA Damage Response, LPS‐stimulated MAPK Signaling, p38 MAPK Signaling, PI3K Signaling in B Lymphocytes, CD40 Signaling, ATM Signaling
BACH1	1	NRF2‐mediated Oxidative Stress Response
ELF1	3	Telomerase Signaling, HGF Signaling, ERK/MAPK Signaling
ELK1	45	ErbB2‐ErbB3 Signaling, Estrogen‐Dependent Breast Cancer Signaling, Corticotropin Releasing Hormone Signaling, HGF Signaling, Glucocorticoid Receptor Signaling, IL‐2 Signaling, IL‐10 Signaling, ERK/MAPK Signaling, Erythropoietin Signaling, IL‐3 Signaling, LPS‐stimulated MAPK Signaling, Cholecystokinin/Gastrin‐mediated Signaling, p38 MAPK Signaling, PI3K Signaling in B Lymphocytes, Gα12/13 Signaling, HMGB1 Signaling, Oncostatin M Signaling, April Mediated Signaling, B Cell Activating Factor Signaling, B Cell Receptor Signaling, Cardiac Hypertrophy Signaling, EGF Signaling, GM‐CSF Signaling, Toll‐like Receptor Signaling, Regulation of IL‐2 Expression in Activated and Anergic T Lymphocytes, Growth Hormone Signaling, PEDF Signaling, IL‐17 Signaling, FLT3 Signaling in Hematopoietic Progenitor Cells, Neuregulin Signaling, PDGF Signaling, ErbB Signaling, RANK Signaling in Osteoclasts, SAPK/JNK Signaling, IGF‐1 Signaling, T Cell Receptor Signaling, Rac Signaling, Renin‐Angiotensin Signaling, IL‐6 Signaling, GNRH Signaling, 14‐3‐3‐mediated Signaling, Relaxin Signaling, CXCR4 Signaling, Acute Phase Response Signaling, Sertoli Cell‐Sertoli Cell Junction Signaling
ETS1	7	Telomerase Signaling, HGF Signaling, ERK/MAPK Signaling, Sumoylation Pathway, B Cell Receptor Signaling, GM‐CSF Signaling, Renal Cell Carcinoma Signaling
GABPA	1	Agrin Interactions at Neuromuscular Junction
HDAC6	10	Telomerase Signaling, Hereditary Breast Cancer Signaling, Huntington's Disease Signaling, Chronic Myeloid Leukemia Signaling, Calcium Signaling, Role of NFAT in Cardiac Hypertrophy, Cell Cycle: G1/S Checkpoint Regulation, Phospholipase C Signaling, Cyclins and Cell Cycle Regulation, Adipogenesis pathway
HDAC8	10	Telomerase Signaling, Hereditary Breast Cancer Signaling, Huntington's Disease Signaling, Chronic Myeloid Leukemia Signaling, Calcium Signaling, Role of NFAT in Cardiac Hypertrophy, Cell Cycle: G1/S Checkpoint Regulation, Phospholipase C Signaling, Cyclins and Cell Cycle Regulation, Adipogenesis pathway
JUN	54	ErbB2‐ErbB3 Signaling, Estrogen‐Dependent Breast Cancer Signaling, Corticotropin Releasing Hormone Signaling, HGF Signaling, Glucocorticoid Receptor Signaling, PCP pathway, IL‐2 Signaling, IL‐10 Signaling, RAR Activation, NRF2‐mediated Oxidative Stress Response, Erythropoietin Signaling, IL‐3 Signaling, Prolactin Signaling, LPS‐stimulated MAPK Signaling, Huntington's Disease Signaling, Sumoylation Pathway, Cholecystokinin/Gastrin‐mediated Signaling, PI3K Signaling in B Lymphocytes, Gα12/13 Signaling, HMGB1 Signaling, April Mediated Signaling, B Cell Activating Factor Signaling, B Cell Receptor Signaling, Thrombopoietin Signaling, Cardiac Hypertrophy Signaling, EGF Signaling, Agrin Interactions at Neuromuscular Junction, Toll‐like Receptor Signaling, CD40 Signaling, Regulation of IL‐2 Expression in Activated and Anergic T Lymphocytes, ATM Signaling, Renal Cell Carcinoma Signaling, JAK/Stat Signaling, IL‐17 Signaling, PDGF Signaling, PPAR Signaling, ErbB Signaling, RANK Signaling in Osteoclasts, SAPK/JNK Signaling, IGF‐1 Signaling, T Cell Receptor Signaling, Rac Signaling, Renin‐Angiotensin Signaling, IL‐6 Signaling, GNRH Signaling, 14‐3‐3‐mediated Signaling, Aryl Hydrocarbon Receptor Signaling, Th2 Pathway, Relaxin Signaling, CXCR4 Signaling, Acute Phase Response Signaling, Sertoli Cell‐Sertoli Cell Junction Signaling, Role of NFAT in Regulation of the Immune Response, Th1 and Th2 Activation Pathway
JUNB	2	PCP pathway, NRF2‐mediated Oxidative Stress Response
JUND	3	Corticotropin Releasing Hormone Signaling, PCP pathway, NRF2‐mediated Oxidative Stress Response
MEF2A	9	Corticotropin Releasing Hormone Signaling, Cholecystokinin/Gastrin‐mediated Signaling, p38 MAPK Signaling, Gα12/13 Signaling, Calcium Signaling, Role of NFAT in Cardiac Hypertrophy, Cardiac Hypertrophy Signaling, Phospholipase C Signaling, Role of NFAT in Regulation of the Immune Response
SMARCC1	5	Glucocorticoid Receptor Signaling, Hereditary Breast Cancer Signaling, RAR Activation, Role of BRCA1 in DNA Damage Response, AMPK Signaling
SMARCC2	5	Glucocorticoid Receptor Signaling, Hereditary Breast Cancer Signaling, RAR Activation, Role of BRCA1 in DNA Damage Response, AMPK Signaling
SP1	9	Telomerase Signaling, ErbB2‐ErbB3 Signaling, Estrogen‐Dependent Breast Cancer Signaling, IL‐10 Signaling, Prolactin Signaling, Huntington's Disease Signaling, Sumoylation Pathway, HMGB1 Signaling, Aryl Hydrocarbon Receptor Signaling
STAT5A	18	ErbB2‐ErbB3 Signaling, Estrogen‐Dependent Breast Cancer Signaling, Glucocorticoid Receptor Signaling, IL‐2 Signaling, RAR Activation, Erythropoietin Signaling, IL‐3 Signaling, Prolactin Signaling, Chronic Myeloid Leukemia Signaling, Oncostatin M Signaling, Thrombopoietin Signaling, Growth Hormone Signaling, JAK/Stat Signaling, FLT3 Signaling in Hematopoietic Progenitor Cells, Neuregulin Signaling, PPAR Signaling, Th2 Pathway, Th1 and Th2 Activation Pathway
TCF12	1	PEDF signaling

^aPathways determined to be significantly enriched in TF dataset, with a −log P‐value of >1.3.