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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Proteomics. 2017 Oct;17(19):10.1002/pmic.201700156. doi: 10.1002/pmic.201700156

Figure 1.

Figure 1

(A) Results of the two-step cluster analysis demonstrating a favorable cluster ratio (<3) and silhouette measure (>0.5) at four fixed clusters. (B) Dendrogram of the hierarchical clustering results (BL: Burkitt’s lymphoma, B-ALL: B cell Acute lymphocytic leukemia, CLL: chronic lympocytic leukemia, T-ALL: T cell Acute lymphocytic leukemia. (C) Graphical distribution of the 247 proteins observed in at least two biological replicates of a cell line (generated using Cytoscape [33]). Color indicates whether the protein is a CD antigen and size is proportional to number of drugs developed against it, as cataloged in ChEMBL, PharmGKB, and Therapeutic Targets Database [34–36].