Table 2.
Summary of adverse events in the meta‐analysis
| Neutropenia | Mucositis | Thrombocytopenia | Anemia | Gastrointestinal reaction | Infection | Overall | |
|---|---|---|---|---|---|---|---|
| Nonsevere |
0.84 (0.69, 1.02) I 2 = 28%, P = 0.09 |
0.98 (0.50, 1.93) I 2 = 0, P = 0.95 |
0.77 (0.61, 0.98) I 2 = 46%, P = 0.03a |
0.91 (0.77, 1.09) I 2 = 34%, P = 0.31 |
0.93 (0.81, 1.06) I 2 = 17%, P = 0.27 |
0.92 (0.46, 1.84) I 2 = 19%, P = 0.82 |
0.88 (0.81, 0.96) I 2 = 13%, P = 0.004a |
| Severe |
0.80 (0.56, 1.13) I 2 = 2%, P = 0.20 |
1.13 (0.50, 2.54) I 2 = 0, P = 0.77 |
1.10 (0.39, 3.12) I 2 = 59%, P = 0.85 |
0.91 (0.50, 1.65) I 2 = 0, P = 0.76 |
0.46 (0.29, 0.73) I 2 = 0, P = 0.0009a |
0.47 (0.11, 2.04) I 2 = 0, P = 0.32 |
0.73 (0.58, 0.92) I 2 = 1%, P = 0.007a |
a
P value less than 0.05.