Table 1.
Conventional Crosslinking | Protocol | Accelerated Crosslinking |
---|---|---|
Yes | Removal of epithelium | Yes |
Isotonic riboflavin 0.1% with dextran 20% solution | Riboflavin solution | Dextran-free riboflavin 0.1% solution |
Every 2 mins for 30mins | Duration of soak | Every 2mins for 10mins |
UV-X, Peschke Meditrade GmbH, Huenenberg, Switzerland | UV illumination device | KXL, Avedro, Inc., Waltham, Massachusetts, MA, USA |
3mW/cm2 for 30 minutes (total energy: 5.4J/cm2). | Illumination protocol | 30 mW/cm2 continuously for 4 minutes (total energy: 7.2J/cm2). |