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. 2017 Aug 29;11:262–272. doi: 10.2174/1874364101711010262

Table 1.

Conventional and accelerated crosslinking protocols.

Conventional Crosslinking Protocol Accelerated Crosslinking
Yes Removal of epithelium Yes
Isotonic riboflavin 0.1% with dextran 20% solution Riboflavin solution Dextran-free riboflavin 0.1% solution
Every 2 mins for 30mins Duration of soak Every 2mins for 10mins
UV-X, Peschke Meditrade GmbH, Huenenberg, Switzerland UV illumination device KXL, Avedro, Inc., Waltham, Massachusetts, MA, USA
3mW/cm2 for 30 minutes (total energy: 5.4J/cm2). Illumination protocol 30 mW/cm2 continuously for 4 minutes (total energy: 7.2J/cm2).