Table 5.

Outcome according to absolute value ranges of HFABP.

Study [ref], year	Covariates included	Risk of higher HFABP in patients with ACS
Viswanathan [12], 2010	Unadjusted	Death or MI HR (95% CI) according to HFABP level HFABP 0.15-3.26 µg/l HR 1, p = <0.001. HFABP 3.27-6.48 µg/l HR 3.41 (1.89 – 6.16) p = 0.001 HFABP 6.49-12.77 µg/l HR 15.67 (8.16-30.07) p = <0.001. HFABP 12.78-151.0 µg/l HR 20.37 (10.38-40.00) p =<0.001.
Kilcullen, [7] 2007	Unadjusted	All-cause mortality HR (95% CI) according to HFABP level HFABP < 6.38µg/l HR 1. HFABP 6.38-12.39µg/l HR 4.45 (2.47-8) p <0.001. HFABP 12.39 – 36.2µg/l HR 8.78 (4.99-15.46) p < 0.001. HFABP > 36.2µg/l HR 11.69 (6.67-20.49) p <0.001.
O Donoghue [13], 2006	Unadjusted	Death rate 10 months (p<0.001) HFABP <8 µg/l 3.1% HFABP 8-16 µg/l 6.9% HFABP >16 µg/l 18% MI rates 10 months (p=0.009) HFABP <8 µg/l 5.6% HFABP 8-16 µg/l 5.5% HFABP >16 µg/l 13.8%
Viswanathan, [12] 2010	Age, DM, HTN, previous HF, Previous MI, HR, ST depression, creatinine, troponin.	Death or MI median 18 month HFABP 0.15 – 3.26 µg/l HR 1, p = 0.003. HFABP 3.27 – 6.48 µg/l HR 0.78 (0.39 – 1.55) p = 0.48. HFABP 6.49 – 12.77 µg/l HR 2.62 (1.30 – 5.28) p = 0.007. HFABP 12.78 – 151.0 µg/l HR 1.54 (0.55 – 4.32) p = 0.41.
Kilcullen, [7] 2007	GRACE risk factors, and inpatient PCI and HS CRP.	HFABP quartiles adjusted for GRACE risk factors plus hs-CRP with TnI as continuous variable. HFABP < 6.38µg/l HR 1. HFABP 6.38-12.39µg/l HR 2.32 (1.25 – 4.30) p = 0.007. HFABP 12.39 – 36.2µg/l HR 3.17 (1.73 – 5.82) p < 0.001. HFABP > 36.2µg/l HR 4.88 (2.67 – 8.93) p <0.001.