Table 2.

PP13 induced increase of venous diameters

Changes in venous diameters in gravid rats at day 21 of pregnancy following previous exposure to slow release of w/t (n = 9) and truncated PP13 (n = 6) compared to saline control (n = 6). The pumps were implanted in pregnancy days 8, and PP13 was detected in the animal blood until day 15. Note that, the closer the vein is to the placenta, the larger the effect. Only w/t PP13 was able to induce enlargement of venous diameters, while the truncated form (delT PP13) was unable to do so. Bolded (w/t PP13) values are significantly different from controls (p < 0.001). Modified from Gizurarson et al., Ref. [128].

Type of vein	Control (n = 6)	PP13 (n = 9)	delT PP13 (n = 6)
	Mean ± SD	Mean ± SD	Mean ± SD
Post-placental vein	0.28 ± 0.07	0.41 ± 0.11	0.24 ± 0.09
Post-myometrial vein	0.55 ± 0.34	0.61 ± 0.14	0.33 ± 0.16
Radial vein	0.75 ± 0.32	0.91 ± 0.32	0.52 ± 0.15