Figure 4.

The Efficacy of Combination Therapy Is Largely Dependent on a T Cell Response

(A) Average tumor volumes for athymic nude mice implanted with M3-9-M or 76-9. These mice were treated with A8301, HSV1716, or the combination thereof as outlined in Figure 2. The data are plotted until the first mouse in each respective treatment group reached endpoint criteria. n = 5 mice per group. (B) Kaplan-Meier survival curves for the athymic nude mice in (A). Error bars represent SD.