Table 1.
Effects of ethylene acetate extract of Bidens pilosa on blood pressure and heart rate
| Parameters | Treatments | ||||
|---|---|---|---|---|---|
| Vehicle (10 ml/kg) | L-NAME | L-NAME + Bp (75 mg/kg) | L-NAME + Bp (150 mg/kg) | L-NAME + Losartan | |
| DBP (mm Hg) | 104.14 ± 7.42 | 158.96 ± 2.29b | 122.22 ± 8.04β | 105.28 ± 8.22β | 123.79 ± 1.32β |
| SBP (mm Hg) | 117.56 ± 8.66 | 180.62 ± 4.08b | 135.64 ± 8.56β | 119.52 ± 8.20β | 137.72 ± 3.20β |
| MABP (mmHg) | 108.61 ± 7.75 | 166.18 ± 2.68b | 126.69 ± 8.12β | 110.03 ± 8.19β | 128.43 ± 1.45β |
| HR (beat /min) | 334.21 ± 10.51 | 311.48 ± 14.14 | 314.02 ± 13.14 | 352.20 ± 15.74 | 345.30 ± 12.82 |
Each value represents a means ± S.E.M. of 6 rats; b P < 0.01, significantly different compared to normal rats. β P < 0.01, significantly different compared to L-NAME hypertensive rats
DBP diastolic blood pressure, SBP systolic blood pressure, MABP mean arterial blood pressure, HRheart rate