Table 2.
Parameters | Treatments | ||||
---|---|---|---|---|---|
Vehicle (10 ml/kg) | L-NAME | L-NAME + Bp (75 mg/kg) | L-NAME +Bp (150 mg/kg) | L-NAME + Los (25 mg/kg) | |
Total Chol (mmol/L) | 1.14 ± 0.10 | 1.22 ± 0.07 | 1.13 ± 0.12 | 1.00 ± 0.14 | 1.18 ± 0.05 |
HDL chol (mmol/L) | 0.91 ± 0.13 | 0.66 ± 0.10a | 0.83 ± 0.11α | 0.72 ± 0.16 | 0.78 ± 0.09 |
LDL chol (mmol/L) | 0.24 ± 0.06 | 0.56 ± 0.08a | 0.30 ± 0.04 | 0.29 ± 0.03β | 0.40 ± 0.12 |
Triglycerides (mmol/L) | 0.61 ± 0.06 | 1.54 ± 0.05b | 0.75 ± 0.27α | 0.33 ± 0.11β | 0.64 ± 0.22β |
Atherogenic index (mmol/L) | 0.34 ± 0.01 | 0.67 ± 0.07a | 0.39 ± 0.08α | 0.28 ± 0.05β | 0.51 ± 0.07 |
Each value represents a means ± S.E.M. of 6 rats; a P < 0.05 bP < 0.01, significantly different compared to normal rats. α P < 0.05, βP < 0.01, significantly different compared to L-NAME hypertensive rats