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. 2017 Oct 10;36:139. doi: 10.1186/s13046-017-0609-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Par3 knockdown inhibits while Par3 overexpression facilitates PC3 cell migration and invasion in vitro. a Stable knockdown of Par3 inhibits both migration and invasion in PC3 cells by transwell assays. Migratory and invasive cells are counted and averaged from five randomly selected fields respectively. Scale Bar: 20 μm b Overexpression of Par3 activates both migration and invasion in PC3 cells by transwell assays. Migratory and invasive cells are counted and averaged from five randomly selected fields respectively. Scale Bar: 20 μm. All data are represented as mean ± SD from triplicate experiments. *: p < 0.05, **: p < 0.01