Table 1.
Comparison of Ld-RAC/AKT-like gene with trypanosomatid and human homologues. Identity and similarity percentages of the full cDNA and protein sequences are shown as compared to the herein reported Ld-RAC/AKT-like gene from L. donovani (MHOM/IN/80/Dd8)
| Species | cDNA % identity | Protein % identity | Protein % similarity |
|---|---|---|---|
| L. donovani (Nepal) | 97.8 | 98.0 | 99.2 |
| L. braziliensis | 89.6 | 92.9 | 94.5 |
| L. infantum | 97.7 | 98.8 | 99.2 |
| L. major | 98.0 | 98.8 | 98.8 |
| L. mexicana | 96.0 | 96.7 | 97.6 |
| L. panamensis | 90.1 | 93.9 | 96.6 |
| T. cruzi | 45.6 | 32.5 | 46.3 |
| T. vivax | 41.8 | 32.9 | 48.1 |
| T. brucei | 42.0 | 34.6 | 48.4 |
| Human AKT1 | 43.9 | 26.5 | 43.2 |
| Human AKT2 | 42.1 | 26.1 | 41.5 |
| Human AKT3 | 43.8 | 25.4 | 40.7 |