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. 2017 Oct 10;474(20):3499–3512. doi: 10.1042/BCJ20170531

Figure 4. In situ localization of BERV-K3 transcript in the skin, liver, kidney, and ileum.

Figure 4.

Bovine tissue sections were purchased from Zymogen (San Diego, CA, U.S.A.). In the skin, BERV-K3 transcript is found in external root and internal root sheath areas of hair follicles and stratum spinosum of epidermis. ORS, outer root sheath; IRS, inner root sheath. In the liver, BERV-K3 is seen in hepatic laminas of lobule areas, particularly in hepatocytes surrounding central veins and ILV, and in interlobular bile ducts of portal canal areas. ILA, interlobular artery; ILB, interlobular bile duct; ILV, interlobular vein. In the kidney, BERV-K3 transcript is found in epithelial cells of renal-collecting ducts and distal convoluted tubules, and in infiltrating lymphocytes around renal-collecting ducts. CD, collecting duct; DCT, distal convoluted tubule; Rc, renal corpuscle. In the ileum, BERV-K3 is seen in intestinal epithelia and enterocytes in glandules, and in PP regions. PP, Peyer's patch. In each, the far right images represent those with the sense-strand cRNA probe.