Table 2.
Hemodynamic Parameters With Exercise
| Exercise Hemodynamics | |||
|---|---|---|---|
| Variable | Group 1 (n=21) Younger | Group 2 (n=19) Older | P Value |
| Peak workload, W | 42±28 | 44±24 | 0.803 |
| Indexed workload, W/kg | 0.46±0.26 | 0.53±0.28 | 0.361 |
| Exercise time, min | 5.2±3.4 | 5.2±2.7 | 0.970 |
| Systolic BP, mm Hg | 188±25 | 196±24 | 0.316 |
| Heart rate, beats/min | 105±20 | 98±20 | 0.314 |
| Mean PAP, mm Hg | 40±9 | 42±9 | 0.427 |
| PCWP, mm Hg | 27±6 | 30±7 | 0.135 |
| Cardiac output, L/min | 10.1±3.3 | 8.5±3.0 | 0.127 |
| Cardiac index, L/min per m2 | 5.0±1.4 | 4.4±1.6 | 0.212 |
| SVR, mm Hg/min per mL−1 | 13.1±6.1 | 14.8±5.9 | 0.360 |
| Mixed venous oxygen saturation, % | 53.3±12.0 | 38.8±9.6 | <0.001* |
| Hemoglobin, g/L | 135.8±15.3 | 133.8±13.8 | 0.689 |
| Arterial oxygen saturation, % | 96.4±2.8 | 96.1±2.6 | 0.73 |
| Arteriovenous oxygen difference | 7.9±2.4 | 10.8±1.8 | <0.001* |
| VO2, mL/min | 824.4±356.0 | 929.6±394.4 | 0.399 |
| VO2, mL/kg per min | 9.1±3.4 | 11.3±5.4 | 0.139 |
| Oxygen delivery | 1849.0±662.9 | 1628.7±707.3 | 0.329 |
| Oxygen extraction ratio, % | 44±12.1% | 60.3±9.1% | <0.001* |
Continuous variables are presented as mean±SD. *P value comparative t test with significance defined as <0.05. BP indicates blood pressure; PAP, pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; SVR, systemic vascular resistance; VO2 , oxygen consumption.