Table 1.
Baseline Variable Summary Statistics: SHHEC Participants by Sex, Aged ≥30, and Free of CVD
| Values Obtained | Men | Women | All | |
|---|---|---|---|---|
| Number of participants | 15 737 | 7552 | 8185 | 15 737 |
| Personal | ||||
| Ageb | 15 737 | 49.0 (8.3) | 49.0 (8.3) | 49.0 (8.3) |
| Sex,b male% | 15 737 | 100 | 0 | 52.0. |
| Years of education | 15 396 | 11.2 (2.8) | 11.1 (2.5) | 11.1 (2.6) |
| Family history of CHD,b % | 15 737 | 25.5 | 31.8 | 28.8 |
| SIMD‐socioeconomic scoreb | 15 737 | 28.0 (21.9) | 28.6 (22.0) | 28.3 (21.9) |
| ASSIGN cardiovascular risk scoreb | 13 444 | 14.8 (10.6) | 9.5 (9.9) | 12.1 (10.6) |
| Smoking | ||||
| Current tobacco smoker, % | 15 737 | 51.6 | 40.2 | 45.7 |
| Cigarettes equivalent,b cigs/d | 15 737 | 9.1 (11.9) | 6.6 (9.6) | 7.8 (10.83) |
| Expired carbon monoxide, ppm | 15 257 | 10.6 (12.5) | 9.0 (11.5) | 9.8 (12.0) |
| Thiocyanate, μmol/La | 13 738a | 57.8 (1.99) | 58.4 (1.98) | 58.1 (1.98) |
| Cotinine, ng/mL | 10 984 | 128 (171) | 103 (152) | 115 (162) |
| Physical measurements | ||||
| Height, m | 15 729 | 1.73 (0.07) | 1.60 (0.06) | 1.66 (0.09) |
| Weight, kg | 15 727 | 77.9 (12.5) | 65.9 (12.6) | 71.6 (13.9) |
| Body mass index, kg/m2 | 15 725 | 26.0 (3.7) | 25.8 (4.8) | 25.9 (4.3) |
| Waist circumference, cm | 4061 | 92.2 (11.6) | 80.5 (12.2) | 85.9 (13.2) |
| Waist/hip ratio | 4061 | 0.92 (0.078) | 0.79 (0.071) | 0.85 (0.096) |
| SBP,b mm Hg | 15 729 | 134.0 (19.4) | 130.5 (21.1) | 132.1 (20.4) |
| DBP, mm Hg | 15 729 | 83.4 (12.0) | 79.6 (11.9) | 81.4 (12.1) |
| Pulse pressure, mm Hg | 15 729 | 50.6 (14.1) | 50.8 (15.1) | 50.7 (14.6) |
| Pulse rate, bpm | 15 661 | 76.5 (13.3) | 78.6 (12.3) | 77.6 (12.9) |
| Diabetes mellitus | ||||
| Diabetes mellitus,b % | 15 737 | 1.6 | 1.4 | 1.5 |
| Glucose, mmol/L (nonfasting) | 12 837 | 5.17 (1.54) | 4.92 (1.36) | 5.04 (1.46) |
| Insulin, μU/mL (nonfasting)c | 12 281 | 11.2 (13.2) | 8.52 (9.60) | 9.83 (11.6) |
| C‐Peptide, mg/mLa, c | 12 365 (13)a | 2.41 (1.92) | 2.14 (1.82) | 2.27 (1.90) |
| Lipids | ||||
| Total cholesterol,b mmol/L | 14 172 | 6.23 (1.16) | 6.40 (1.30) | 6.32 (1.24) |
| HDL‐cholesterol,b mmol/L | 13 460 | 1.35 (0.37) | 1.63 (0.43) | 1.49 (0.42) |
| Non‐HDL‐cholesterol, mmol/L | 13 459 | 4.88 (1.14) | 4.78 (1.21) | 4.88 (1.18) |
| Triglycerides, mmol/La | 14 158 | 1.91 (1.77) | 1.41 (1.69) | 1.64 (1.76) |
| LDL‐cholesterol, mmol/Lc | 10 833 | 2.65 (1.27) | 2.75 (1.19) | 2.70 (1.16) |
| Apolipoprotein A, g/Lc | 12 867 | 1.49 (0.26) | 1.64 (0.30) | 1.57 (0.29) |
| Apolipoprotein B, g/Lc | 12 866 | 1.18 (0.30) | 1.13 (0.32) | 1.15 (0.31) |
| Lipoprotein (a), mg/dLa, c | 12 773 (88)a | 9.55 (3.89) | 11.81 (3.38) | 10.64 (3.64) |
| Inflammatory | ||||
| hsC‐reactive protein, mg/La, c | 12 847 | 1.53 (2.99) | 1.27 (3.10) | 1.39 (3.06) |
| Fibrinogen, g/L | 13 101 | 2.75 (0.80) | 2.86 (0.81) | 2.81 (0.81) |
| Homocysteine, μmol/Lc | 12 843 | 16.0 (6.6) | 14.0 (5.7) | 14.9 (6.2) |
| Ferritin, μmol/La, c | 12 319 (22)a | 103.0 (2.64) | 38.0 (2.97) | 62.0 (3.14) |
| Cardiac | ||||
| hsTroponin I, pg/mLa, c | 11 527 (427)a | 3.76 (2.60) | 2.25 (3.80) | 2.97 (3.29) |
| NT‐pro‐BNP, pg/mLa, c | 10 507 | 31.7 (2.94) | 61.5 (2.45) | 44.7 (2.83) |
| Diet related | ||||
| 25‐Hydroxyvitamin D raw, nmol/Lc | 11 603 | 44.3 (22.7) | 39.2 (19.7) | 41.6 (21.3) |
| 25‐Hydroxyvitamin D adj, nmol/Lc | 11 603 | 44.0 (19.3) | 39.4 (17.9) | 41.6 (18.7) |
| Vitamin B12, pg/mLc | 12 355 | 425 (180) | 423 (191) | 424 (186) |
| γ‐Glutamyl transferase, units/La | 12 835 | 31.4 (1.92) | 18.5 (1.79) | 24.1 (1.96) |
| Renal related | ||||
| Uric acid, mmol/L | 14 178 | 320 (66) | 243 (62) | 281 (75) |
| Creatinine, mmol/L | 11 837 | 95.9 (12.9) | 81.4 (11.0) | 88.6 (14.0) |
| Cystatin‐C, mg/Lc | 12 868 | 0.760 (0.143) | 0.716 (0.165) | 0.738 (0.156) |
Missing values are omitted. Percentages are shown for categorical factors. Arithmetic means and standard deviations are shown for continuous variables with some exceptions.aCHD indicates coronary heart disease; CVD, cardiovascular disease; DBP, diastolic blood pressure; HDL, high‐density lipoprotein; SBP, systolic blood pressure; SHHEC, Scottish Heart Health Extended Cohort; SIMD, Scottish Index of Multiple Deprivation.
Geometric means and standard deviations because of positive skew. For these geometric calculations any 0 values (number in parentheses) are set to 0.01 units.
ASSIGN risk score factor.
Assayed in the MORGAM/BiomarCaRE project after long‐term storage of serum at −40°C.