Table 2.
Sensitivity, Specificity, and Predictive Value for Baseline Symptom Questionnaires and ECG Ischemia Versus 20‐Year Disease Outcomes, Sexes Combined
| See Key | Rose Angina Questionnaire | Edinburgh Claudication Questionnaire | Electrocardiographic “Possible Ischemia” (Minnesota Code) | ||||
|---|---|---|---|---|---|---|---|
| End Point | CHD | PAD | CHD | PAD | CHD | PAD | |
| True positive N | a | 279 | 37 | 104 | 47 | 382 | 58 |
| False positive N | b | 581 | 823 | 231 | 288 | 783 | 1107 |
| False negative N | c | 2819 | 462 | 2994 | 452 | 2716 | 441 |
| True negative N | d | 12 058 | 14 415 | 12 408 | 14 950 | 11 856 | 14 131 |
| Sensitivity, % | a×100/(a+c) | 9.0 | 7.4 | 3.4 | 9.4 | 12.3 | 11.6 |
| Specificity, % | d×100/(b+d) | 95.4 | 94.6 | 98.2 | 98.1 | 93.8 | 92.7 |
| Positive predictive value, % | a×100/(a+b) | 32.4 | 4.3 | 31.0 | 14.0 | 32.8 | 5.0 |
| Negative predictive value, % | d×100/(c+d) | 81.1 | 96.9 | 80.6 | 97.1 | 81.4 | 97.0 |
| Prediction ratio | ppv/(100−npv) | 1.7 | 1.4 | 1.6 | 4.8 | 1.8 | 1.6 |
CHD indicates coronary heart disease; PAD, peripheral arterial disease.