Table 1.
Clinical and Demographic Data of Study Population
| All Patients (N=161) | Living Donors (n=49) | Deceased Donors (n=112) | P Value | Standard Criteria Donors (n=60) | Expanded Criteria Donors (n=52) | P Value | |
|---|---|---|---|---|---|---|---|
| Recipient age, y | 50 (49–52) | 48 (44–51) | 51 (49–53) | 0.1 | 47 (45–50) | 56 (54–58) | <0.001 |
| Men/women | 110/51 | 37/49 | 73/112 | 0.1 | 40/60 | 33/52 | 0.7 |
| BMI, kg/m2 | 24 (24–25) | 25 (23–26) | 24 (23–25) | 0.3 | 24 (23–25) | 24 (23–25) | 0.7 |
| Time on dialysis, mo | 30 [10–51] | 7 [1–24] | 37 [21–66] | <0.001 | 39 [23–64] | 36 [19–70] | 0.9 |
| Pre‐KT diabetes mellitus, % | 12 | 10 | 12 | 0.7 | 7 | 19 | 0.05 |
| Pre‐KT dyslipidemia, % | 47 | 43 | 51 | 0.5 | 38 | 60 | 0.03 |
| Pre‐KT former tobacco, % | 22 | 26 | 24 | 0.9 | 22 | 23 | 0.9 |
| Preemptive KT, No. | 10 | 9 | 1 | <0.001 | 2 | 0 | 0.2 |
| Donor age, y | 51 (49–53) | 50 (47–53) | 52 (49–54) | 0.4 | 42 (40–45) | 63 (61–65) | <0.001 |
| DGF, % | 14 | 0 | 22 | <0.001 | 17 | 25 | 0.2 |
| Acute rejection, % | 9 | 7 | 11 | 0.3 | 15 | 6 | 0.1 |
| NODAT, % | 19 | 10 | 23 | 0.05 | 18 | 29 | 0.2 |
| ARB or ACEI, % | 67 | 65 | 69 | 0.6 | 65 | 73 | 0.005 |
| mGFR M3, mL/min per 1.73 m2 | 53 [43–64] | 52 [44–60] | 55 [44–66] | 0.8 | 58 [49–70] | 51 [39–61] | 0.05 |
| mGFR M12, mL/min per 1.73 m2 | 54 [45–68] | 57 [46–65] | 52 [42–69] | 0.3 | 60 [46–71] | 47 [38–60] | 0.001 |
| uPCR M3, g/mmol | 0.03 [0.02–0.04] | 0.03 [0.02–0.04] | 0.02 [0.02–0.04] | 0.8 | 0.02 [0.02–0.04] | 0.02 [0.02–0.05] | 0.5 |
| uPCR M12, g/mmol | 0.02 [0.01–0.03] | 0.02 [0.01–0.03] | 0.02 [0.01–0.04] | 0.9 | 0.02 [0.01–0.03] | 0.02 [0.01–0.04] | 0.4 |
Recipient age, donor age, and body mass index (BMI) values are expressed as mean (95% confidence interval). Time on dialysis, measured glomerular filtration rate (mGFR), and urine protein/creatinine ratio (uPCR) values are expressed as median [interquartile range]. ACEI indicates angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; DGF, delayed graft function; KT, kidney transplantation; M3, month 3 after kidney transplantation; M12, month 12 after kidney transplantation; NODAT, new‐onset diabetes mellitus after transplantation.