Table 3.

Characteristics of Patients With Single and Double Mutations

	Single Variant (n=35)	Double Variant (n=4)	P Value
Sex, male:female	15:20	3:1	0.32
Age of onset, y	0.5±0.2	0.001±0.001	0.43
CHF at diagnosis, n (%)	26 (74.3)	4 (100)	0.56
Family history, n (%)	12 (34.2)	0	0.29
LVEF, %	36.9±2.2	37.5±3.8	0.93
LVDD z score	1.51±0.19	2.31±0.34	0.19

Double heterozygous variants: MYH7 and JUP, MYH7 and BMPR1A, TPM1 and SGCD, and TAZ and KCNE3. CHF indicates congestive heart failure; LVDD, left ventricular end‐diastolic dimension; LVEF, left ventricular ejection fraction.