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Characteristics of Patients With Sarcomere and Nonsarcomere Mutations
| Sarcomere Variant (n=24) | Nonsarcomere Variant (n=11) | P Value | |
|---|---|---|---|
| Sex male:female | 8:16 | 3:8 | 0.99 |
| Age of onset, y | 0.7±0.3 | 0.15±0.07 | 0.26 |
| CHF at diagnosis, n (%) | 15 (62.5) | 10 (91) | 0.12 |
| Family history, n (%) | 6 (34.8) | 6 (54.5) | 0.13 |
| LVEF, % | 39.4±2.3 | 31.8±4.7 | 0.11 |
| LVDD z score | 1.24±0.2 | 2.1±0.4 | 0.04 |
CHF indicates congestive heart failure; LVDD, left ventricular end‐diastolic dimension; LVEF, left ventricular ejection fraction.
