Table 3.

Cox Regression Analysis for Post–Radiation Therapy CVEs

Characteristic	HR (95% CI)	P Value
HPV status	4.82 (1.6–14.3)	0.005
HPV status, age, male sex	4.37 (1.5–13.1)	0.008
HPV status, prior CVE	4.58 (1.5–13.7)	0.006
HPV status, prior CVE, hypertension	4.43 (1.5–13.2)	0.008
HPV status, prior CVE, age	4.41 (1.5–13.1)	0.008
HPV status, prior CVE, age, male sex	4.33 (1.4–13.1)	0.009
HPV status, prior CVE, age, male sex, neck dissection, radiation dose, oropharyngeal cancer, laryngeal cancer	5.36 (1.7–16.7)	0.004

CI indicates confidence interval; CVE, cerebrovascular event; HPV, human papillomavirus; HR, hazard ratio.