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. 2017 Aug 28;6(9):e006535. doi: 10.1161/JAHA.117.006535

Table 3.

Multiple Linear Regression Analysis of the Association Between Cytomegalovirus pp65‐Specific CD8+ T Cells and PWV

Regression Coefficient 95% CI P Value
Pp65‐specific IFN‐γ secretion (R 2=0.519)
Age, y 0.004 0.004 to 0.005 <0.001
Female sex −0.021 −0.039 to −0.002 0.031
DM history 0.026 0.010 to 0.042 0.001
Smoking history 0.009 −0.003 to 0.021 0.161
BMI, kg/m2 −0.002 −0.005 to 0.000 0.067
SBP, mm Hg 0.002 0.001 to 0.002 <0.001
Creatinine, mg/dL 0.003 −0.008 to 0.014 0.579
HDL‐cholesterol, mg/dL 0.000 −0.001 to 0.000 0.237
hsCRP, mg/L 0.001 −0.001 to 0.003 0.361
Percent IFN‐γ+ in CD8+ T cellsa 0.020 0.007 to 0.033 0.003
pp65‐specific TNF‐α secretion (R 2=0.517)
Age, y 0.004 0.004 to 0.005 <0.001
Female sex −0.021 −0.040 to −0.002 0.030
DM history 0.025 0.010 to 0.041 0.002
Smoking history 0.008 −0.004 to 0.021 0.181
BMI, kg/m2 −0.002 −0.005 to 0.000 0.084
SBP, mm Hg 0.002 0.001 to 0.002 <0.001
Creatinine, mg/dL 0.004 −0.007 to 0.015 0.453
HDL‐cholesterol, mg/dL 0.000 −0.001 to 0.000 0.256
hsCRP, mg/L 0.001 −0.001 to 0.003 0.351
Percent TNF‐α+ in CD8+ T cellsa 0.021 0.006 to 0.036 0.006
Pp65‐specific CD107a expression (R 2=0.517)
Age, y 0.004 0.003 to 0.005 <0.001
Female sex −0.021 −0.040 to −0.002 0.027
DM history 0.027 0.011 to 0.043 0.001
Smoking history 0.009 −0.004 to 0.021 0.174
BMI, kg/m2 −0.002 −0.004 to 0.000 0.116
SBP, mm Hg 0.002 0.001 to 0.002 <0.001
Creatinine, mg/dL 0.004 −0.007 to 0.015 0.466
HDL‐cholesterol, mg/dL 0.000 −0.001 to 0.000 0.330
hsCRP, mg/L 0.001 −0.001 to 0.003 0.314
Percent CD107a+ in CD8+ T cellsa 0.033 0.010 to 0.056 0.006

BMI indicates body mass index; CI, confidence interval; DM, diabetes mellitus; HDL, high‐density lipoprotein; hsCRP, high‐sensitivity C‐reactive protein; IFN‐γ, interferon‐γ; PWV, pulse wave velocity; SBP, systolic blood pressure; TNF‐α, tumor necrosis factor‐α.

a

Log‐transformed.