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. 2017 Sep 11;6(9):e006936. doi: 10.1161/JAHA.117.006936

Figure 2.

Figure 2

Mice deficient in PEA‐15 (phosphoprotein enriched in astrocytes 15; PEA‐15 −/−) have an increased rate of development of neointimal hyperplasia. A, Representative hematoxylin and eosin–stained sections of mouse carotid arteries from either PEA‐15 −/− and wild‐type (WT) mice at 3, 7, and 14 days after wire‐induced vascular injury. Scale bar=100 μm. B, Mean data on the intima:media ratio in injured carotid arteries from PEA‐15 −/− or wild‐type mice at 3, 7, and 14 days following vascular injury (statistical significance is shown only for injured vs sham vessels), n=6. *P<0.05 and **P<0.01 using 2‐way ANOVA and Bonferroni post hoc test. C, Mean data directly comparing the rate of intima development in injured carotid arteries from PEA‐15 −/− and WT mice, n=6. *P<0.05 using 1‐way ANOVA and Newman–Keuls post hoc test.