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. 2017 Aug 31;6(9):e007024. doi: 10.1161/JAHA.117.007024

Figure 2.

Figure 2

UVB irradiation reduces the severity of Ang II–induced AAA. A, Representative photographs showing macroscopic features of aneurysms induced by Ang II. No animals infused with normal saline developed aneurysm (left specimen). Infusion of Ang II in apolipoprotein E–deficient mice developed AAA (middle and right). Arrowheads indicate abdominal and thoracic aneurysms. Scale bar=1 mm. B, Incidence of AAA in UVB‐irradiated (n=38) and nonirradiated (n=42) mice. C, Severity of aneurysm in UVB‐irradiated (n=27) and nonirradiated (n=17) mice. Error bars represent standard error in (B and C). D, Maximal diameter of abdominal aorta in UVB‐irradiated (n=27) and nonirradiated (n=17) mice. In the box‐and‐whisker plot, middle line represents median value, box indicates interquartile range (25th–75th percentiles), and range bars show maximum and minimum. **P<0.01. AAA indicates abdominal aortic aneurysm; Ang II, angiotensin II; UVB, ultraviolet B.