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Results of the Mendelian Randomization analyses using different estimators.
| Analysis Method | OR | 95% CI | P-value | P-value (intercept) |
|---|---|---|---|---|
| Inverse-Variance Weighted (IVW) | 1.018 | 0.98–1.06 | 0.354 | |
| Weighted Median | 1.044 | 0.98–1.12 | 0.200 | |
| MR-Egger regression | 1.052 | 0.94–1.17 | 0.363 | 0.513 |
The intercept P-value can be interpreted as an estimate of the average (horizontal) pleiotropic effect across the genetic variants.
