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. 2017 Oct 9;7:12814. doi: 10.1038/s41598-017-12828-z

Table 1.

Summary of the calculated K m and IC 50 values.

Transporter Compound Mice Kidney Slice (µM) Expression Model (µM)
Octn1 Ergothioneine (K m) 69.8 ± 27.6 4.6822
Verapamil (IC 50) 151 ± 46 271 ± 44
Octn2 Verapamil (IC 50) 363 ± 142 94.1 ± 8.9
Sglt1/2 Phloridzin (IC 50) 0.265 ± 0.084 0.299 (Sglt1)33
0.0726 (Sglt2)33
Pept1/2 Gly-Sar (K m) 161 ± 17 600 (PEPT1)37
79.5 (PEPT2)31