Table 1.

Differentially expressed microRNAs in murine lung tissue following 4 weeks of cigarette smoke exposure.

Up-regulated in CS-exposed mice	miRBase release 21	Fold change	Adjusted p-value
mmu-miR-135b	mmu-miR-135b-5p	4.110	0.015
mmu-miR-138	mmu-miR-138-5p	2.160	0.015
mmu-miR-21	mmu-miR-21a-5p	1.747	0.015
mmu-miR-155	mmu-miR-155-5p	1.580	0.021
mmu-miR-31	mmu-miR-31-5p	1.238	0.024
Down-regulated in CS-exposed mice	miRBase release 21	Fold change	Adjusted p-value
mmu-miR-322x	mmu-miR-322-3p	1.695	0.015
mmu-miR-351	mmu-miR-351-5p	1.585	0.024
mmu-miR-434-3p	mmu-miR-434-3p	1.531	0.024
mmu-miR-136	mmu-miR-136-5p	1.531	0.021

First column: annotation of miRNA during microRNA profiling; Second column: annotation of miRNA according to miRBase release 21.