Table 6. Risk prediction models for CKD progression in 999 participants and all-cause mortality in 1,732 participants using different estimating equations for eGFR.
| Risk prediction | Estimating equation | Odds ratio or hazard ratio (95% CI) | P value | AUROC |
|---|---|---|---|---|
| Models for KDIGO CKD progression | eGFRcreat | 0.984 (0.971–0.998) | 0.023 | 0.722 |
| eGFRcys | 0.982 (0.971–0.993) | 0.001 | 0.726 | |
| eGFRcreat-cys | 0.978 (0.965–0.991) | 0.001 | 0.726 | |
| Models for all-cause mortality | eGFRcreat | 0.973 (0.960–0.986) | <0.001 | |
| eGFRcys | 0.975 (0.963–0.987) | <0.001 | ||
| eGFRcreat-cys | 0.967 (0.954–0.981) | <0.001 |
All progression models are adjusted for age, sex, urine albumin-to-creatinine ratio, haemoglobin, bicarbonate, and diabetes. All odds ratios given per ml/min/1.73 m2. All survival models are adjusted for age, sex, urine albumin-to-creatinine ratio, haemoglobin, albumin, bicarbonate, diabetes, and previous cardiovascular disease. All hazard ratios are given per ml/min/1.73 m2.
AUROC, area under the receiver operating characteristic curve; CKD, chronic kidney disease; creat, creatinine; cys, cystatin C; creat-cys, creatinine and cystatin C; eGFR, estimated glomerular filtration rate; KDIGO, Kidney Disease Improving Global Outcomes.