Fig 2.

Change in LCQ (A) and VAS (B) scores according to time and group. The LCQ and VAS scores are significantly improved through 8 weeks in the PPI group, but not in the placebo group (between-group comparison: LCQ score, P < 0.001; VAS score, P = 0.063). PPI, proton pump inhibitor; LCQ, Leicester Cough Questionnaire; VAS, visual analog scale; SE, standard error. * P-value < 0.05 according to time; † P-value < 0.05 according to time between the 2 groups; obtained by linear mixed model analysis after adjustment for age, sex, hypertension, and atopy.