Figure 5.

In vivo ¹⁹F MR spectrum in a mouse tumor model. FLT (200 mM, 100 μL) was injected into tail veins. (a) Anatomical ¹H MR images of the mouse were obtained using fast spin echo sequence with the voxel of interest in the tumor (5 × 5 × 5 mm³). Time-course of ¹⁹F MR spectra at (b) 25 min after injection (a.i.) (−175.9 ppm) and (c) 90 min a.i. (−175.08 ppm). ¹⁹F MRS data were acquired with Point-REsolved Spectroscopy (PRESS) using TR 3000 ms, TE 15 ms, averages 512, scan time 25 min.