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. 2017 Oct 10;12(10):e0185948. doi: 10.1371/journal.pone.0185948

Fig 2. Chemical cycle of a single motor head.

Fig 2

(A) The ATP hydrolysis can take place both in a MT-attached (M) or MT-detached (m) head; the asterisk denotes states with the linker in the pre-powerstroke position and ATP, ADP.Pi, and ADP denote the nucleotides bound to the head. The 5-state ATPase cycle of the dynein motor [16] is enclosed by the dashed frame. The ovals highlight the effective states of the simplified cycle in our model (grey ovals: M* and m*, white ovals: M and m). (B) The 2-state effective cycle of our model.