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. 2017 Oct 10;89(15):1569–1577. doi: 10.1212/WNL.0000000000004490

Figure 1. Temporal dynamics of white matter hyperintensities (WMH) progression.

Figure 1

(A) Change in WMH volume (mL) over 3 time points by age at individual level. (B) Acceleration of WMH volume change over 2 follow-up periods (mL/y) by age at individual level. (C) Change in WMH volume (mL) over 3 time points by age at individual level stratified by baseline WMH severity. Baseline WMH severity was classified as mild (Fazekas 0–1; n = 211), moderate (Fazekas 2; n = 33), or severe (Fazekas 3; n = 20). Smoothed curves using loess smoothing express average WMH change with increasing age.