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Time course of change in rate of coronary flow (CF), outflow of LDH and CK enzymes in control, control ischemia, Vit C and different doses of Achillea wilhelmsii extract (100, 200 and 400 mg/kg; Ext 100, Ext 200, Ext 400) treated rat groups during ischemia–reperfusion. The data provided are mean ± SEM. +p < 0.05, ++p < 0.01 and +++p < 0.001 compared to control group. *p < 0.05, **p < 0.01 and **p < 0.01 compared to control ischemia group.
