Table 3.
Effect of B.retusa extract on hematological parameter of rats treated with Freund's complete adjuvant.
| Group | Dose (mg/kg) | WBC count (103/mm3) | RBC | Platelet count (105/mm3) | ESR (mm/hr) |
|---|---|---|---|---|---|
| Normal | – | 8.50 ± 0.165 | 6.02 ± 0.529 | 2.35 ± 0.223 | 3.78 ± 0.185 |
| Control | – | 12.21 ± 0.288 | 4.25 ± 0.232 | 3.46 ± 0.180 | 5.54 ± 0.490 |
| PE | 200 | 11.32 ± 0.460 | 4.74 ± 0.320 | 2.89 ± 0.151 | 4.99 ± 0.209∗ |
| 400 | 8.98 ± 0.417∗∗∗ | 5.87 ± 0.198** | 2.58 ± 0.077 | 4.06 ± 0.439∗∗∗ | |
| EA | 200 | 11.29 ± 0.718 | 4.60 ± 0.035 | 2.94 ± 0.219 | 4.87 ± 0.496 |
| 400 | 9.25 ± 0.563∗∗∗ | 5.66 ± 0.340** | 2.61 ± 0.217 | 4.25 ± 0.323∗∗ | |
| ACE | 200 | 11.04 ± 0.659∗ | 4.57 ± 0.385 | 2.57 ± 0.201 | 5.15 ± 0.447 |
| 400 | 10.45 ± 1.228∗∗∗ | 5.22 ± 0.057** | 2.70 ± 0.144 | 4.16 ± 0.167∗∗∗ | |
| Diclofenac | 13.5 | 9.28 ± 0.320∗∗∗ | 5.63 ± 0.415** | 2.48 ± 0.283 | 4.44 ± 0.468∗∗ |
The observations are given as Mean SD. n = 6; *P < 0.05, **P < 0.01 ***P < 0.001. Compared with saline treated control group (ANOVA followed by multiple Dunnet's test).