Table 2.
Distribution of genotypes between cases and controls
| Polymorphism | Case (N = 775) | Control (N = 805) | P |
|---|---|---|---|
| TNF -238G > A | 0.308 | ||
| GG | 732 (94.5%) | 745 (92.5%) | |
| GA | 41 (5.3%) | 57 (7.1%) | |
| AA | 2 (0.3%) | 3 (0.4%) | |
| TNF -308G > A | 0.307 | ||
| GG | 683 (88.1%) | 726 (90.2%) | |
| GA | 86 (11.1%) | 76 (9.4%) | |
| AA | 6 (0.8%) | 3 (0.4%) | |
| IL1B -511 T > C | 0.079 | ||
| TT | 213 (27.5%) | 257 (31.9%) | |
| TC | 384 (49.5%) | 392 (48.7%) | |
| CC | 178 (23.0%) | 156 (19.4%) | |
| IL1B 3954C > T | 0.777 | ||
| CC | 602 (77.7%) | 632 (78.5%) | |
| CT | 168 (21.7%) | 166 (20.6%) | |
| TT | 5 (0.6%) | 7 (0.9%) | |
| IL6 -174G > C | 0.135 | ||
| GG | 484 (62.5%) | 463 (57.5%) | |
| GC | 248 (32.0%) | 291 (36.1%) | |
| CC | 43 (5.5%) | 51 (6.3%) | |
| IL6 -634C > G | < 0.001 | ||
| CC | 554 (71.5%) | 478 (59.4%) | |
| CG | 197 (25.4%) | 277 (34.4%) | |
| GG | 24 (3.1%) | 50 (6.2%) | |
| IL10 -1082A > G | 0.186 | ||
| AA | 683 (88.1%) | 685 (85.1%) | |
| AG | 88 (11.4%) | 113 (14.0%) | |
| GG | 4 (0.5%) | 7 (0.9%) | |
| IFNG 874A > T | 0.589 | ||
| AA | 613 (79.1%) | 621 (77.1%) | |
| AT | 154 (19.9%) | 173 (21.5%) | |
| TT | 8 (1.0%) | 11 (1.4%) |