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. 2017 Oct 10;14:34. doi: 10.1186/s12014-017-9169-6

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Proteins that showed an increasing trend in Proseek^® values in the four patient groups. The logarithmic output of the top 12 biomarkers that showed an increasing trend in values from healthy, to benign, to early stage serous ovarian cancer, to late stage serous ovarian cancer were graphed as quantile plots: CA125, HE4, MK, KLK6, hK11, CXCL13, FR-alpha, IL-6, TNFSF14, FADD, PRSS8, and FUR. Outliers are defined as any value higher or lower than 1.5 multiplied by the interquartile range. A complete ranking of all 92 proteins is shown in Additional file 1