. Author manuscript; available in PMC: 2018 Dec 1.

Published in final edited form as: Arthritis Care Res (Hoboken). 2017 Nov 6;69(12):1789–1798. doi: 10.1002/acr.23229

Table 3.

Association between BMI and ln(CRP) before and after adjusting for disease activity or fat mass

	Women
	Baseline Model β (95% CI)	Baseline + Joint count/patient global β (95% CI)	Baseline + FMI-Z β (95% CI)

BC Cohort (n = 169)	0.061 (0.035, 0.088)^***	0.062 (0.036, 0.088)^***	−0.049 (−0.118, 0.021)
BMI (per 1 kg/m²)	0.061 (0.035, 0.088)^***	0.062 (0.036, 0.088)^***	−0.049 (−0.118, 0.021)
VARA Cohort (n = 135, obs = 773)	0.029 (0.010, 0.046)^**	0.026 (0.007, 0.044)^**
BMI (per 1 kg/m²)	0.029 (0.010, 0.046)^**	0.026 (0.007, 0.044)^**

	Men

	Baseline Model β (95% CI)	Baseline + Joint Counts/Patient Global β (95% CI)	Baseline + FMI-Z β (95% CI)

BC Cohort (n = 131)	−0.015 (−0.052, 0.022)	−0.013 (−0.050, 0.025)	−0.039 (−0.128, 0.049)
BMI (per 1 kg/m²)	−0.015 (−0.052, 0.022)	−0.013 (−0.050, 0.025)	−0.039 (−0.128, 0.049)
VARA Cohort (n = 1424, obs = 8148)	−0.005 (−0.014, 0.005)	−0.003 (−0.012, 0.006)
BMI (per 1 kg/m²)	−0.005 (−0.014, 0.005)	−0.003 (−0.012, 0.006)

^**

p <0.01,

^***

p < 0.001.

Baseline model adjusted for age, race, smoking status, and study site (in BC). Disease activity adjusted by including swollen joint count, tender joint count, and patient global scores in multivariable models. BMI: body mass index; BC: 3 pooled body composition studies of patients with rheumatoid arthritis; VARA: Veterans Affairs Rheumatoid Arthritis Registry. FMI-Z: DXA derived fat mass index z-score (mean of 0 and standard deviation of 1 in a reference population)