Table 3. Factors associated with viral suppression at one year from ART initiation, paediatric analysis using modified intention to treat method, N=1968.

	Total patients	VL <1000 copies/mL	Univariate			Multivariate
			OR	95%CI	p	OR	95%CI	p
Age at ART initiation (years)					<0.001			<0.001
<1.5 years	569	364	Ref			Ref
1.5-4	441	355	2.32	(1.74, 3.11)	<0.001	2.33	(1.73, 3.14)	<0.001
5-9	492	405	2.62	(1.97, 3.50)	<0.001	2.79	(2.06, 3.78)	<0.001
10-14	395	311	2.09	(1.55, 2.80)	<0.001	2.32	(1.70, 3.16)	<0.001
15-17	71	56	2.10	(1.16, 3.81)	0.014	2.34	(1.28, 4.27)	0.006
Sex
Male	977	731	Ref			Ref
Female	991	760	1.11	(0.90, 1.36)	0.333	1.11	(0.89, 1.37)	0.350
Prior AIDS-defining illness					0.199			0.613
No	127	111	Ref			Ref
Yes	38	30	0.54	(0.21, 1.38)	0.199	0.78	(0.30, 2.03)	0.613
Unknown	1803	1350	0.43	(0.25, 0.73)	0.002	0.53	(0.31, 0.92)	0.024
Pre-ART CD4 %					0.021			<0.001
<10%	396	291	Ref			Ref
10-14%	228	175	1.19	(0.81, 1.74)	0.366	1.43	(0.97, 2.11)	0.074
15-24%	419	356	2.04	(1.44, 2.89)	<0.001	2.38	(1.67, 3.41)	<0.001
≥25%	293	226	1.22	(0.86, 1.73)	0.274	1.81	(1.24, 2.64)	0.002
Missing	632	443	0.85	(0.64, 1.12)	0.242	1.11	(0.83, 1.49)	0.491
HIV mode of exposure					0.238			0.164
Perinatal	1592	1197	0.76	(0.49, 1.19)	0.238	0.72	(0.46, 1.14)	0.164
Sexual behaviour	129	103	Ref			Ref
Other/Unknown	247	191	0.86	(0.51, 1.45)	0.575	0.86	(0.50, 1.48)	0.591
Region					0.083			0.384
Asia-Pacific	229	185	Ref			Ref
Caribbean, Central and South America	60	49	1.06	(0.51, 2.20)	0.877	1.02	(0.47, 2.21)	0.959
South Africa	1679	1257	0.71	(0.50, 1.00)	0.051	0.80	(0.56, 1.14)	0.217

Note: Values in bold represent significant covariates in the adjusted model.

Abbreviations: OR – odds ratio, 95%CI – 95% confidence interval, ART – antiretroviral therap