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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Neuropharmacology. 2017 Sep 5;126:151–157. doi: 10.1016/j.neuropharm.2017.09.005

Figure 3. Systemic administration of the nNOS inhibitor NPA attenuated NO efflux elicited in the msNAc during electrical train stimulation of the fimbria.

Figure 3

Top: Representative recordings showing the effects of train stimulation (20 sec, 50 Hz, 750 μA, 0.5 ms) of the fimbria delivered prior to, and 40 min after, systemic administration of NPA (20 mg/kg, i.p.). Dashed vertical lines indicate the initiation and termination of the stimulation period. Bottom: The mean ± S.E.M. increase in NO efflux evoked by train stimulation was significantly reduced 40 min after NPA administration (***p<0.005). A trend towards a decrease in NO efflux evoked by train stimulation of the fimbria was still evident 60 min post-drug (#p=0.067). Results are expressed as the mean ± SEM of data normalized to pre-vehicle/NPA values and are derived from n=4–5 rats per group.