Table 1.
Effect of vanillic acid on body weight and tumour incidence in normal and MNNG treated rats
| Groups | Body weight (g) | Tumor incidence | |||
|---|---|---|---|---|---|
| Initial | Final | No. of animals | No. of animals bearing tumor | Average | |
| Normal | 175.03 ± 8.75a | 193.18 ± 13.5c | 6 | – | 0 |
| MNNG | 190.32 ± 15.2b | 160.26 ± 8.01a | 6 | 6 | 100 % |
| VA | 167.42 ± 10.02a | 185.42 ± 12.97b | 6 | – | 0 |
| VA + MNNG (pre-treatment) | 190.32 ± 15.2b | 180.35 ± 10.82b | 6 | 1 | 30 % |
| MNNG + VA (co-treatment) | 200.14 ± 12.02c | 170.24 ± 11.91d | 6 | 3 | 50 % |
Values are means ± SD from six rats in each group. Values not sharing a common superscript differ significantly at p < 0.05 (DMRT)