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. 2017 Oct 10;7:12919. doi: 10.1038/s41598-017-13186-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The transcriptional regulation mode of Bmsage and Fibrohexamerin gene. Formaldehyde-assisted isolation of regulatory elements (FAIRE; 0–30) and RNA (Fibrohexamerin 0–50,000, Bmsage 0–200) signals for 10-kb upstream regions from (a) Bmsage and (b) Fibrohexamerin. Pink peaks are silk gland FAIRE-seq and RNA-seq peaks. Blue peaks are BmE FAIRE-seq and RNA-seq peaks. Other colored shadows show locations of known transcription factor binding sites, and each color corresponds to a particular transcription factor.