Figure 3.
Localization of IL-10-expressing cells in the mouse cochlea. (A) Immunolabeling shows appearance of IL-10-positive cells (black arrowheads) in the stria vascularis 1 d after LPS injection. IL-10 labeling is also noted in the lower part of the spiral ligament (asterisk). (B,C) On 5 d after LPS injection, IL-10-positive cells are observed in the spiral ligament (black arrow), but not in the stria vascularis. IL-10-positive cells are distributed in the spiral limbus, spiral ganglion area (#), suprastrial area and osseous spiral lamina (white block arrows). SM, scala media; ST, scala tympani; SV, scala vestibule. Scale bar: 100 μm. (D) Surface preparation showing IL-10-positive cells (white arrows) in the cochlear lateral wall tissue. IL-10 is also labeled in a capillary-like structure. Scale bar: 25 μm.