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. 2017 Jul 22;22(6):731–741. doi: 10.1007/s10741-017-9640-5

Table 2.

Meta-analysis results for depression, quality of life, mortality and hospitalisations

Outcome Number of studies Number of participants Statistical method used Effect estimate, mean, risk ratio (95% CI) p value Heterogeneity, I 2 (%)
Depression (initially after CBT)
 BDI-II 4 203 Standardised mean difference (fixed effects) −0.35 (−0.63 to −0.07) 0.01 0
 All scales 5 235 Standardised mean difference (fixed effects) −0.34 (−0.60 to −0.08) 0.01 0
Depression (3 months after CBT)
 BDI-II 4 174 Standardised mean difference (fixed effects) −0.30 (−0.61 to −0.00) 0.05 0
 All scales 5 204 Standardised mean difference (fixed effects) −0.32 (−0.59 to −0.04) 0.03 0
QoL (initially after CBT)
 MLHFQ 4 88 Standardised mean difference (fixed effects) −0.25 (−0.68 to 0.18) 0.26 52
 All scales 5 220 Standardised mean difference (fixed effects) −0.31 (−0.58 to −0.05) 0.02 38
QoL (3 months after CBT)
 MLHFQ 4 78 Standardised mean difference (fixed effects) −0.13 (−0.58 to 0.33) 0.58 0
 All scales 5 197 Standardised mean difference (fixed effects) −0.22 (0.51 to 0.06) 0.12 0
Mortality
 All-cause mortality 4 135 Risk ratio (fixed effects) 1.05 (0.44 to 2.52) 0.92 0
Hospitalisations
 All-cause hospitalisations 4 257 Risk ratio (fixed effects) 0.99 (0.75 to 1.32) 0.96 0

BDI-II Beck Depression Inventory-revised, CBT cognitive behavioural therapy CI confidence intervals, MLHFQ Minnesota Living with Heart Failure Questionnaire, QoL quality of life