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ATM−/−/Trp53−/− mice are radiosensitive, but have a different phenotype compared to Prkdcscid/scid/Trp53−/− mice. (a) Positional counts of γH2A.X positive cells 24 h after 8 Gy; ATM−/−(n=2), ATM−/−/Trp53−/−(n=2). Data from other genotypes are replotted here from Figure 2. (b) H&E staining of ATM−/−/p53−/− mouse at day 3 left, and day 4 right. Note evidence of Paneth cells at both time points (arrowheads)
