. 2017 Sep 27;2017:8796760. doi: 10.1155/2017/8796760

Table 1.

A prime-boost protocol based on BCG-priming and IFN-alpha protects adult mice from M. tuberculosis aerosol challenge.

Vaccine	Lung CFUs^a	Lung protection		Spleen CFUs^a	Spleen protection
Vaccine	Lung CFUs^a	control versus BCG		Spleen CFUs^a	control versus BCG
Control	5.1 ± 1.27			4.7 ± 0.71
BCG	4.0 ± 0.99	1.1^∗		3.7 ± 0.78	1.0
IFN-α	4.8 ± 0.64	0.3		4.4 ± 0.14	0.3^∗
BCG-IFN-α	3.7 ± 0.37	1.4^∗	0.3^∗∗	2.8 ± 0.67	1.9^∗	0.9^∗∗

^aData are represented as mean ± standard deviations of the log₁₀ –transformed bacterial (CFUs) of M. tuberculosis per organ. Aerosol challenge. Protection is calculated with respect to control of vaccination (BCG) and with respect to PBS-immunized newborn mice (control). The data reported are ^∗significant at P < 0.05 with respect to control mice and ^∗∗significant at P < 0.05 with respect to BCG control of vaccination with no boost. One representative of a total of two independent experiments is shown.