Figure 2.
Cell viability in vitro is reduced under hypoxia treated by TPZ, but TPZ response is not altered by glucose concentration. (A) HM-7, H1299, HT28 and RIF-1 cell viability under normoxia treated by TPZ, measured by CellTiter-Glo (CTG) luminescence cell viability assay. (B) The same treatment under hypoxia. (C) The comparison of EC50 values under normoxia versus hypoxia condition. (D) The ratio of EC50 values between normoxia and hypoxia. (E) Cell viability as a function of oxygenation and glucose concentration for HM-7 cells under TPZ treatment. (F) Cell viability as a function of oxygenation and glucose concentration for HT29 cells under TPZ treatment. Data in 2C-2F are presented as mean ± standard deviation.