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TPZ and Anti-VEGF used in combination produced a strong suppression of tumor growth. (A) At Day 7 post treatment, significant reduction of tumor volume was seen in B20.4.1.1 group, TPZ group and combo group as measured by caliper. Tumor volume for the combo group was also significantly reduced relative to the monotherapy groups. (B) Percent change in body weight over the 7-day study. *P < .05, **P < .01, ***P < .0001 with respect to control (Dunnett's).
