Table 10.
TYPE | Barriers/limitations | Challenges and opportunities |
---|---|---|
Experimental | Dataset | High number of subjects must be recruited to validate the results of the studies. |
Dataset | Patients with mild impairments (HY = 1) should be investigated to promote early diagnosis. | |
Dataset | Age-matched controls should be involved, because motor performance vary with age. | |
Technological | Acceptability | The system should be developed with consideration for patients' requirements and needs. |
Usability | The system should be easy to use and eventually provide user-friendly interfaces both for clinician and patients. | |
Portability and unobtrusiveness | The system should be wireless and non-invasive for use at home or outdoors without limitations for the patients. The number of sensors used and their placement over the body should address the trade-off between accuracy in measurements and obtrusiveness. | |
Long-term monitoring | The system should ensure long-term operation. Long-term battery and low-power solutions have to be adopted, especially for home-monitoring applications for advanced patients with motor fluctuations. | |
Measurements | The system should provide quantitative, accurate, precise, objective, and reliable measurements of the symptoms analyzed to actively support the clinician in diagnosis and management of the pathology. | |
The system should be able to recognize different stages of the disease as well as to evaluate changes due to pharmacological treatments. | ||
Clinical | Availability for use in clinical practice | - Accuracy, precision, reliability, and dependability of the system should be ensured. - Objective support for clinical examination and assessment should be validated, complying with traditional medical scales. - Improvements for patients' management should be efficiently demonstrated. |